Publications

Fan TH, Li JQ, Minatovicz B, Soha E, Sun L, Patel S, Chaudhuri B, Bogner R. Phase-Field Modeling of Freeze Concentration of Protein Solutions. Polymers. 2019;11(1):10.

Moseson DE, Taylor LS. The application of temperature-composition phase diagrams for hot melt extrusion processing of amorphous solid dispersions to prevent residual crystallinity. International journal of pharmaceutics. 2018 Dec 20;553(1-2):454-66.

Moseson DE, Mugheirbi NA, Stewart AA, Taylor LS. Nanometer-scale residual crystals in a hot melt extruded amorphous solid dispersion: characterization by transmission electron microscopy. Crystal Growth & Design. 2018 Oct 26;18(12):7633-40.

Beringhs AO, Minatovicz BC, Zhang GG, Chaudhuri B, Lu X. Impact of Porous Excipients on the Manufacturability and Product Performance of Solid Self-Emulsifying Drug Delivery Systems. AAPS PharmSciTech. 2018 Oct 1;19(7):3298-310.

Sun WJ, Rantanen J, Sun CC. Ribbon density and milling parameters that determine fines fraction in a dry granulation. Powder Technology. 2018 Oct 1;338:162-7.

Sun WJ, Kothari S, Sun CC. The relationship among tensile strength, Young’s modulus, and indentation hardness of pharmaceutical compacts. Powder Technology. 2018 May 15;331:1-6.

Kulkarni SS, Suryanarayanan R, Rinella Jr JV, Bogner RH. Mechanisms by which crystalline mannitol improves the reconstitution time of high concentration lyophilized protein formulations. European Journal of Pharmaceutics and Biopharmaceutics. 2018 Oct 1;131:70-81.

Ong HJ, Pinal R. Drug Solubilization by Means of a Surface-Modified Edible Biopolymer Enabled by Hot Melt Extrusion. Journal of Pharmaceutical Sciences. 2018 Jan 1;107(1):402-11.

Xie T, Taylor LS. Effect of temperature and moisture on the physical stability of binary and ternary amorphous solid dispersions of celecoxib. Journal of Pharmaceutical Sciences. 2017 Jan 1;106(1):100-10.

Sarkar S, Minatovicz B, Thalberg K, Chaudhuri B. Development of a rational design space for optimizing mixing conditions for formation of adhesive mixtures for dry-powder inhaler formulations. Journal of Pharmaceutical Sciences. 2017 Jan 1;106(1):129-39.

Sarkar S, Minatovicz B, Thalberg K, Chaudhuri B. Mechanistic investigation of mixing and segregation of ordered mixtures: experiments and numerical simulations. Drug Development and Industrial Pharmacy. 2017 Oct 3;43(10):1677-85.

Osei-Yeboah F, Lan Y, Sun CC. A top coating strategy with highly bonding polymers to enable direct tableting of multiple unit pellet system (MUPS). Powder Technology. 2017 Jan 1;305:591-6.

Kalra A, Tishmack P, Lubach JW, Munson EJ, Taylor LS, Byrn SR, Li T. Impact of supramolecular aggregation on the crystallization kinetics of organic compounds from the supercooled liquid state. Molecular Pharmaceutics. 2017 May 17;14(6):2126-37.

Sun WJ, Sun CC. Ribbon thickness influences fine generation during dry granulation. International Journal of Pharmaceutics. 2017 Aug 30;529(1-2):87-8.

Mistry P, Amponsah-Efah KK, Suryanarayanan R. Rapid assessment of the physical stability of amorphous solid dispersions. Crystal Growth & Design. 2017 Apr 7;17(5):2478-85.

Xie T, Taylor LS. Dissolution performance of high drug loading celecoxib amorphous solid dispersions formulated with polymer combinations. Pharmaceutical Research. 2016 Mar 1;33(3):739-50.

Xie T, Taylor LS. Improved release of celecoxib from high drug loading amorphous solid dispersions formulated with polyacrylic acid and cellulose derivatives. Molecular Pharmaceutics. 2016 Feb 2;13(3):873-84.

Ochoa M, Jiang H, Park JH, Otte A, Pinal R, Ziaie B. Nanoparticle-enabled wireless monitoring and characterization of physical degradation kinetics in pharmaceutical gelatin films. Sensors and Actuators A: Physical. 2016 Apr 15;241:238-44.

Mistry P, Suryanarayanan R. Strength of drug–polymer interactions: implications for crystallization in dispersions. Crystal Growth & Design. 2016 Jul 27;16(9):5141-9.

Mehta M, McKenna GB, Suryanarayanan R. Molecular mobility in glassy dispersions. The Journal of Chemical Physics. 2016 May 28;144(20):204506.

Mehta M, Suryanarayanan R. Accelerated physical stability testing of amorphous dispersions. Molecular Pharmaceutics. 2016 Jul 14;13(8):2661-6.

Mehta M, Ragoonanan V, McKenna GB, Suryanarayanan R. Correlation between molecular mobility and physical stability in pharmaceutical glasses. Molecular Pharmaceutics. 2016 Mar 4;13(4):1267-77.

Mehta M, Kothari K, Ragoonanan V, Suryanarayanan R. Effect of water on molecular mobility and physical stability of amorphous pharmaceuticals. Molecular Pharmaceutics. 2016 Mar 22;13(4):1339-46.

Osei-Yeboah F, Sun CC. Tabletability modulation through surface engineering. Journal of Pharmaceutical Sciences. 2015 Aug 1;104(8):2645-8.

Mehtala JG, Kulczar C, Lavan M, Knipp G, Wei A. Cys34-PEGylated human serum albumin for drug binding and delivery. Bioconjugate Chemistry. 2015 May 8;26(5):941-9.

Kleppe MS, Forney-Stevens KM, Haskell RJ, Bogner RH. Mathematical models to explore potential effects of supersaturation and precipitation on oral bioavailability of poorly soluble drugs. The AAPS Journal. 2015 Jul 1;17(4):902-17.

Hsieh YL, Taylor LS. Salt stability-effect of particle size, relative humidity, temperature and composition on salt to free base conversion. Pharmaceutical Research. 2015 Feb 1;32(2):549-61.

Hsieh YL, Merritt JM, Yu W, Taylor LS. Salt stability–the effect of pHmax on salt to free base conversion. Pharmaceutical Research. 2015 Sep 1;32(9):3110-8.

Diaz IT, Ghaly ES. Near Infrared Spectroscopy Method: Effect Of Drying Parameters On Ibuprofen Granules Phase Transformation.

Kumar S, Xu X, Gokhale R, Burgess DJ. Formulation parameters of crystalline nanosuspensions on spray drying processing: a DoE approach. International Journal of Pharmaceutics. 2014 Apr 10;464(1-2):34-45.

Kumar S, Gokhale R, Burgess DJ. Sugars as bulking agents to prevent nano-crystal aggregation during spray or freeze-drying. International Journal of Pharmaceutics. 2014 Aug 25;471(1-2):303-11.

Kumar S, Gokhale R, Burgess DJ. Quality by design approach to spray drying processing of crystalline nanosuspensions. International Journal of Pharmaceutics. 2014 Apr 10;464(1-2):234-42.

Boksa K, Otte A, Pinal R. Matrix‐Assisted Cocrystallization (MAC) Simultaneous Production and Formulation of Pharmaceutical Cocrystals by Hot‐Melt Extrusion. Journal of Pharmaceutical Sciences. 2014 Sep;103(9):2904-10.

Abiad MG, Campanella OH, Carvajal MT. Effect of spray drying conditions on the physicochemical properties and enthalpy relaxation of α-lactose. International Journal of Food Properties. 2014 Jul 3;17(6):1303-16.

Kothari K, Ragoonanan V, Suryanarayanan R. Influence of molecular mobility on the physical stability of amorphous pharmaceuticals in the supercooled and glassy states. Molecular Pharmaceutics. 2014 Aug 8;11(9):3048-55.

Kothari K, Ragoonanan V, Suryanarayanan R. Dielectric Spectroscopy of Small Molecule Pharmaceuticals—Effect of Sample Configuration. Journal of Pharmaceutical Sciences. 2014 Oct;103(10):3190-6.

Kothari K, Ragoonanan V, Suryanarayanan R. The role of drug–polymer hydrogen bonding interactions on the molecular mobility and physical stability of nifedipine solid dispersions. Molecular Pharmaceutics. 2014 Nov 26;12(1):162-70.

Kothari K, Ragoonanan V, Suryanarayanan R. The role of polymer concentration on the molecular mobility and physical stability of nifedipine solid dispersions. Molecular Pharmaceutics. 2015 Apr 20;12(5):1477-84.

M. Rodriguez, E.S. Ghaly. Optimization and Manufacturing of Lipid-Surfactant Nanoparticles: Implication Physicochemical Properties and Drug Release. Proceeding in the International Symposium of Controlled Release and Bioactive Materials, IL, USA, July 2014.

M.E. Laboy Cruz, E.S. Ghaly. Tablets Compaction of Lipid Nanoparticles: Impact on Physicochemical Properties and Phase Transformation. Proceeding in the International Symposium of Controlled Release and Bioactive Materials, IL, USA, July 2014.

Naik S, Feng Y, Chaudhuri B. Experiment and model-based investigation of comminution in a hammer mill. International Journal of Computational Methods and Experimental Measurements. 2014 Dec 31;2(4):362-73.

Wang J, Ghaly ES. Mediated Liposome for Gene Delivery to Mice Brain Part I. Design and Characterization of Liposome-DNA Complexes. Global Journal of Medical Research. 2013 May 2.

CONCEPCION-CRUZ SA, GHALY ES. development of NIR method for determination of rheological behavior and drug content of semisolid containing different ratios of lipid to aqueous phase.

Sahni EK, Chaudhuri B. Numerical simulations of contact drying in agitated filter-dryer. Chemical Engineering Science. 2013 Jun 28;97:34-49.

Sahni EK, Bogner RH, Chaudhuri B. Systematic investigation of parameters affecting the performance of an agitated filter‐dryer. Journal of pharmaceutical sciences. 2013 Jul;102(7):2198-213.

Roth WJ, Kissinger CB, McCain RR, Cooper BR, Marchant-Forde JN, Vreeman RC, Hannou S, Knipp GT. Assessment of juvenile pigs to serve as human pediatric surrogates for preclinical formulation pharmacokinetic testing. The AAPS journal. 2013 Jul 1;15(3):763-74.

Osei‐Yeboah F, Sun CC. A pitfall in analyzing powder compactibility data using nonlinear regression. Journal of pharmaceutical sciences. 2013 Mar;102(3):1135-6.

Naik S, Malla R, Shaw M, Chaudhuri B. Investigation of comminution in a Wiley Mill: Experiments and DEM Simulations. Powder technology. 2013 Mar 1;237:338-54.

Keleş Ö, García RE, Bowman KJ. Deviations from Weibull statistics in brittle porous materials. Acta Materialia. 2013 Nov 1;61(19):7207-15.

Keleş Ö, García RE, Bowman KJ. Stochastic failure of isotropic, brittle materials with uniform porosity. Acta Materialia. 2013 May 1;61(8):2853-62.

Janaswamy S, Gill KL, Campanella OH, Pinal R. Organized polysaccharide fibers as stable drug carriers. Carbohydrate polymers. 2013 Apr 15;94(1):209-15.

G.L. Pastrano, and E.S. Ghaly. Physicochemical Characterization of Spray Dried Formulations Containing Amorphous Drug. International Journal of Pharmacy and Pharmaceutical Sciences, 4(4): 563-570 (2012).

Chakravarty P, Suryanarayanan R, Govindarajan R. Phase transformation in thiamine hydrochloride tablets: influence on tablet microstructure, physical properties, and performance. Journal of pharmaceutical sciences. 2012 Apr;101(4):1410-22.

Sahni E, Hallisey J, Morgan B, Strong J, Chaudhuri B. Quantifying drying performance of a filter dryer: Experiments and simulations. Advanced Powder Technology. 2012 Mar 1;23(2):239-49.

Shi L, Feng Y, Sun CC. Initial moisture content can profoundly affect properties of powder prepared using high shear wet granulation. Int J Pharm. 2011;416:43-8.

Yamauchi M, Lee EH, Otte A, Byrn SR, Carvajal MT. Contrasting the surface and bulk properties of anhydrate and dehydrated hydrate materials. Crystal Growth & Design. 2011 Jan 19;11(3):692-8.

Wanapun D, Kestur US, Taylor LS, Simpson GJ. Single particle nonlinear optical imaging of trace crystallinity in an organic powder. Analytical chemistry. 2011 May 20;83(12):4745-51.

Trasi NS, Boerrigter SX, Byrn SR, Carvajal TM. Investigating the effect of dehydration conditions on the compactability of glucose. International journal of pharmaceutics. 2011 Mar 15;406(1-2):55-61.

Thommes M, Ely DR, Carvajal MT, Pinal R. Improvement of the dissolution rate of poorly soluble drugs by solid crystal suspensions. Molecular pharmaceutics. 2011 Mar 28;8(3):727-35.

Shi L, Feng Y, Sun CC. Massing in high shear wet granulation can simultaneously improve powder flow and deteriorate powder compaction: A double-edged sword. European Journal of Pharmaceutical Sciences. 2011 May 18;43(1-2):50-6.

Shi L, Feng Y, Sun CC. Origin of profound changes in powder properties during wetting and nucleation stages of high-shear wet granulation of microcrystalline cellulose. Powder technology. 2011 Apr 10;208(3):663-8.

Qian KK, Bogner RH. Spontaneous crystalline-to-amorphous phase transformation of organic or medicinal compounds in the presence of porous media, part 1: thermodynamics of spontaneous amorphization. Journal of pharmaceutical sciences. 2011 Jul 1;100(7):2801-15.

Padilla AM, Pikal MJ. The study of phase separation in amorphous freeze‐dried systems, part 2: Investigation of raman mapping as a tool for studying amorphous phase separation in freeze‐dried protein formulations. Journal of pharmaceutical sciences. 2011 Apr;100(4):1467-74.

Padilla AM, Ivanisevic I, Yang Y, Engers D, Bogner RH, Pikal MJ. The study of phase separation in amorphous freeze‐dried systems. Part I: Raman mapping and computational analysis of XRPD data in model polymer systems. Journal of pharmaceutical sciences. 2011 Jan;100(1):206-22.

Otte A, Carvajal MT. Assessment of milling-induced disorder of two pharmaceutical compounds. Journal of pharmaceutical sciences. 2011 May 1;100(5):1793-804.

Kaushal AM, Vangala VR, Suryanarayanan R. Unusual effect of water vapor pressure on dehydration of dibasic calcium phosphate dihydrate. Journal of pharmaceutical sciences. 2011 Apr;100(4):1456-66.

S. A. Hailu and R. H. Bogner. Complex Effects of Drug/Silicate Ratio, Solid-State Equivalent pH, and Moisture on Chemical Stability of Amorphous Quinapril Hydrochloride Coground with Silicates. Journal of Pharmaceutical Sciences, 100: 1503-1515 (2011).

K. K. Arora, N. G. Tayade and R. Suryanarayanan. Unintended Water Mediated Cocrystal Formation in Carbamazepine and Aspirin Tablets. Molecular Pharmaceutics, 8: 982-989 (2011).

B. Q. Wang and M. J. Pikal. The Impact of Thermal Treatment on the Stability of Freeze Dried Amorphous Pharmaceuticals: I. Dimer Formation in Sodium Ethacrynate. Journal of Pharmaceutical Sciences, 99: 663-682 (2010).

B. Wang, M. T. Cicerone, Y. Aso and M. J. Pikal. The Impact of Thermal Treatment on the Stability of Freeze-Dried Amorphous Pharmaceuticals: II. Aggregation in an IgG1 Fusion Protein. Journal of Pharmaceutical Sciences, 99: 683-700 (2010).

M. N. Slipchenko, H. T. Chen, D. R. Ely, Y. Jung, M. T. Carvajal and J. X. Cheng. Vibrational imaging of tablets by epi-detected stimulated Raman scattering microscopy. Analyst, 135: 2613-2619 (2010).

A. C. F. Rumondor and L. S. Taylor. Effect of Polymer Hygroscopicity on the Phase Behavior of Amorphous Solid Dispersions in the Presence of Moisture. Molecular Pharmaceutics 7: 477-490 (2010).

A. C. F. Rumondor, H. Konno, P. J. Marsac and L. S. Taylor. Analysis of the Moisture Sorption Behavior of Amorphous Drug-Polymer Blends. Journal of Applied Polymer Science 117: 1055-1063 (2010).

A. C. F. Rumondor, M. J. Jackson and L. S. Taylor. Effects of Moisture on the Growth Rate of Felodipine Crystals in the Presence and Absence of Polymers. Crystal Growth & Design 10: 747-753 (2010).

S. M. Patel, S. Chaudhuri and M. J. Pikal. Choked flow and importance of Mach I in freeze-drying process design. Chemical Engineering Science 65: 5716-5727 (2010).

Y. Miyako, Y. Zhao, K. Takeshima, T. Kataoka, T. Handa and R. Pinal. Solubility of hydrophobic compounds in water–cosolvent mixtures: relation of solubility with water–cosolvent interactions. J. Pharm. Sci. 99: 293-302 (2010).

Y. Miyako, N. Khalef, K. Matsuzaki and R. Pinal. Solubility enhancement of hydrophobic compounds by cosolvents: Role of solute hydrophobicity on the solubilization effect. Int. J. Pharm. 393: 48-54 (2010).

L. J. Mauer and L. S. Taylor. Deliquescence of pharmaceutical systems. Pharmaceutical Development and Technology 15: 582-594 (2010).

C. Mao, S. P. Chamarthy, S. R. Byrn and R. Pinal. Theoretical and Experimental Considerations on the Enthalpic Relaxation of Organic Glasses using Differential Scanning Calorimetry. Journal of Physical Chemistry B 114: 269-279 (2010).

S. A. Hailu and R. H. Bogner. Solid-State Surface Acidity and pH-Stability Profiles of Amorphous Quinapril Hydrochloride and Silicate Formulations. Journal of Pharmaceutical Sciences 99: 2786-2799 (2010).

K. Greco and R. Bogner. Crystallization of Amorphous Indomethacin during Dissolution: Effect of Processing and Annealing. Molecular Pharmaceutics 7: 1406-1418 (2010).

S. P. Chamarthy and R. Pinal. Another unusual property of water: It increases the glass transition temperature of a glassy polymer. In D. Reid, T. Sajjaanantakul, P. J. Lillford, and S. Charoenrein (eds), Water Properties in Food, Health, Pharmaceutical and Biological Systems: ISOPOW 10 (D. Reid, T. Sajjaanantakul, P. J. Lillford, and S. Charoenrein, eds), Wiley-Blackwell, Ames, Iowa, USA, 2010, pp. 401-409.

S. P. Chamarthy, N. Khalef, N. Trasi, A. Bakri, M. T. Carvajal and R. Pinal. The effect of dehydration conditions on the functionality of anhydrous amorphous raffinose. Eur. J. Pharm. Sci. 40: 171-178 (2010).

S. P. Chamarthy, F. X. Diringer and R. Pinal. The plasticization-antiplasticization threshold of water in microcrystalline cellulose. A perspective based on bulk free volume. In D. Reid, T. Sajjaanantakul, P. J. Lillford, and S. Charoenrein (eds), Water Properties in Food, Health, Pharmaceutical and Biological Systems: ISOPOW 10 (D. Reid, T. Sajjaanantakul, P. J. Lillford, and S. Charoenrein, eds), Willey-Blackwell, Ames, Iowa, USA, 2010, pp. 301-314.

P. Chakravarty, R. Govindarajan and R. Suryanarayanan. Investigation of Solution and Vapor Phase Mediated Phase Transformation in Thiamine Hydrochloride. Journal of Pharmaceutical Sciences 99: 3941-3952 (2010).

P. Chakravarty, R. T. Berendt, E. J. Munson, V. G. Young, R. Govindarajan and R. Suryanarayanan. Insights into the Dehydration Behavior of Thiamine Hydrochloride (Vitamin B-1) Hydrates: Part I. Journal of Pharmaceutical Sciences 99: 816-827 (2010).

P. Chakravarty, R. T. Berendt, E. J. Munson, V. G. Young, R. Govindarajan and R. Suryanarayanan. Insights Into the Dehydration Behavior of Thiamine Hydrochloride (vitamin B-1) Hydrates: Part II. Journal of Pharmaceutical Sciences 99: 1882-1895 (2010).

S. Bose and R. H. Bogner. Solvent less visible light-curable coating: II. Drug release, mechanical strength and photostability. International Journal of Pharmaceutics 393: 41-47 (2010).

S. Bose and R. H. Bogner. Solvent less visible light-curable coating: I. Critical formulation and processing parameters. International Journal of Pharmaceutics 393: 32-40 (2010).

M. G. Abiad, D. C. Gonzalez, B. Mert, O. H. Campanella and M. T. Carvajal. A novel method to measure the glass and melting transitions of pharmaceutical powders. International Journal of Pharmaceutics 396: 23-29 (2010).

Paroma Chakravarty and Raj Suryanarayanan. Characterization and Structure Analysis of Thiamine Hydrochloride Methanol Solvate. Cryst. Growth Des. 10: 4414-4420 (2010).

J. J. Schwegman, J. F. Carpenter and S. L. Nail. Evidence of Partial Unfolding of Proteins at the Ice/Freeze-Concentrate Interface by Infrared Microscopy. Journal of Pharmaceutical Sciences 98: 3239-3246 (2009).

A. C. F. Rumondor, L. A. Stanford and L. S. Taylor. Effects of Polymer Type and Storage Relative Humidity on the Kinetics of Felodipine Crystallization from Amorphous Solid Dispersions. Pharmaceutical Research 26: 2599-2606 (2009).

A. C. F. Rumondor, I. Ivanisevic, S. Bates, D. E. Alonzo and L. S. Taylor. Evaluation of Drug-Polymer Miscibility in Amorphous Solid Dispersion Systems. Pharmaceutical Research 26: 2523-2534 (2009).

T. Miyazaki, K. Sivaprakasam, J. Tantry and R. Suryanarayanan. Physical Characterization of Dibasic Calcium Phosphate Dihydrate and Anhydrate. Journal of Pharmaceutical Sciences 98: 905-916 (2009).

R. H. Howard, C. Alonso-Moreno, L. M. Broomfield, D. L. Hughes, J. A. Wright and M. Bochmann. Synthesis and structures of complexes with axially chiral isoquinolinyl-naphtholate ligands. Dalton Transactions 8667-8682 (2009).

S. A. Hailu and R. H. Bogner. Effect of the pH Grade of Silicates on Chemical Stability of Coground Amorphous Quinapril Hydrochloride and its Stabilization Using pH-Modifiers. Journal of Pharmaceutical Sciences 98: 3358-3372 (2009).

S. P. Chamarthy, R. Pinal and M. T. Carvajal. Elucidating raw material variability – Importance of surface properties and functionality in pharmaceutical powders. AAPS PharmSciTech 10: 780-788 (2009).

H. Wikstrom, J. Rantanen, A. D. Gift and L. S. Taylor. Toward an understanding of the factors influencing anhydrate-to-hydrate transformation kinetics in aqueous environments. Crystal Growth & Design 8: 2684-2693 (2008).

H. Wikstrom, W. J. Carroll and L. S. Taylor. Manipulating theophylline monohydrate formation during high-shear wet granulation through improved understanding of the role of pharmaceutical excipients. Pharmaceutical Research 25: 923-935 (2008).

R. Pinal. Entropy of Mixing and the Glass Transition of Amorphous Mixtures. Entropy 10: 207-223 (2008).

M. Papp, C. P. Pujara and R. Pinal. Monitoring of high-shear granulation using acoustic emission: Predicting granule properties. J. Pharm. Innov. 3: 113-122 (2008).

Y. Miyako, H. Tai, K. Ikeda, K. R. and R. Pinal. Solubility screening on a series of structurally related compounds.  Cosolvent-induced changes on the activity coefficient of hydrophobic solutes. Drug Dev. Ind. Pharm. 34: 499 – 505 (2008).

S. A. Luthra, M. J. Pikal and M. Utz. Solid state C-13 NMR investigation of impact of annealing in lyophilized glasses. Journal of Pharmaceutical Sciences 97: 4336-4346 (2008).

S. A. Luthra, I. M. Hodge, M. Utz and M. J. Pikal. Correlation of Annealing with Chemical Stability in Lyophilized Pharmaceutical Glasses. Journal of Pharmaceutical Sciences 97: 5240-5251 (2008).

S. A. Luthra, I. M. Hodge and M. J. Pikal. Investigation of the impact of annealing on global molecular mobility in glasses: Optimization for stabilization of amorphous pharmaceuticals. Journal of Pharmaceutical Sciences 97: 3865-3882 (2008).

S. P. Chamarthy and R. Pinal. Plasticizer concentration and the performance of polymeric drug delivery systems. Colloids Surf. A 331: 25-30 (2008).

S. P. Chamarthy and R. Pinal. Moisture induced antiplasticization in microcrystalline cellulose compacts. Tablets & Capsules 5: 22-33 (2007).

S. P. Chamarthy, A. Otte, D. R. Ely, O. K. Valet, J. Langridge and M. T. Carvajal. Why powders don’t behave the way we want? Understanding how surfaces of phamraceutical powders influence functionality. In R. N. Dalby, P. R. Byron, J. Peart, and J. D. Suman (eds), Respiratory Drug Delivery Europe 2007. (R. N. Dalby, P. R. Byron, J. Peart, and J. D. Suman, eds), Davis Healthcare Interational Publishing, LLC, Paris, France, 2007, pp. 321-324.

Jaidev S. Tantry, Jitesh Tank, Raj Suryanarayanan. Processing-Induced Phase Transitions of Theophylline—Implications on the Dissolution of Theophylline Tablets. Journal of Pharmaceutical Sciences 96: 1434–1444 (2007).

X. L. C. Tang, S. L. Nail and M. J. Pikal. Evaluation of manometric temperature measurement (MTM), a process analytical technology tool in freeze drying, Part III: Heat and mass transfer measurement. AAPS PharmSciTech 7: (2006).

X. L. C. Tang, S. L. Nail and M. J. Pikal. Evaluation of manometric temperature measurement, a process analytical technology tool for freeze-drying: Part II Measurement of dry-layer resistance. AAPS PharmSciTech 7: (2006).

X. L. Tang, S. L. Nail and M. J. Pikal. Evaluation of manometric temperature measurement, a process analytical technology tool for freeze-drying: Part I, product temperature measurement. AAPS PharmSciTech 7: (2006).

A. K. Salameh and L. S. Taylor. Physical stability of crystal hydrates and their anhydrates in the presence of excipients. J. Pharm. Sci. 95: 446-461 (2006).

A. K. Salameh and L. S. Taylor. Deliquescence-induced caking in binary powder blends. Pharmaceutical Development and Technology 11: 453-464 (2006).

S. Romero-Torres, J. D. Perez-Ramos, K. R. Morris and E. R. Grant. Raman spectroscopy for tablet coating thickness quantification and coating characterization in the presence of strong fluorescent interference. Journal of Pharmaceutical and Biomedical Analysis 41: 811-819 (2006).

S. Rambhatla, S. Tchessalov and M. J. Pikal. Heat and mass transfer scale-up issues during freeze-drying, III: Control and characterization of dryer differences via operational qualification tests. Aaps Pharmscitech 7: (2006).

D. Ely, S. Chamarthy and M. T. Carvajal. An investigation into low dose blend uniformity and segregation determination using NIR spectroscopy. Colloids and Surfaces a-Physicochemical and Engineering Aspects 288: 71-76 (2006).

S. P. Chamarthy, M. T. Carvajal and R. Pinal. Moisture induced antiplasticization of microcrystalline cellulose, IUFoST 13th World Congress of Food Science and Technology, IUFoST, Nantes, France, 2006, pp. 1385-1386.

Y. G. Zhang and D. J. W. Grant. Similarity in structures of racemic and enantiomeric ibuprofen sodium dihydrates. Acta Crystallographica Section C-Crystal Structure Communications 61: M435-M438 (2005).

G. G. Z. Zhang and D. J. W. Grant. Formation of liquid inclusions in adipic acid crystals during recrystallization from aqueous solutions. Crystal Growth & Design 5: 319-324 (2005).

H. Wikstrom, I. R. Lewis and L. S. Taylor. Comparison of sampling techniques for in-line monitoring using Raman spectroscopy. Applied Spectroscopy 59: 934-941 (2005).

H. Wen, K. R. Morris and K. Park. Study on the interactions between polyvinylpyrrolidone (PVP) and acetaminophen crystals: Partial dissolution pattern change. Journal of Pharmaceutical Sciences 94: 2166-2174 (2005).

X. L. Tang and M. J. Pikal. Measurement of the kinetics of protein unfolding in viscous systems and implications for protein stability in freeze-drying. Pharmaceutical Research 22: 1176-1185 (2005).

X. L. Tang and M. J. Pikal. The effect of stabilizers and denaturants on the cold denaturation temperatures of proteins and implications for freeze-drying. Pharmaceutical Research 22: 1167-1175 (2005).

X. L. Tang, S. L. Nail and M. J. Pikal. Freeze-drying process design by manometric temperature measurement: Design of a smart freeze-dryer. Pharm. Res. 22: 685-700 (2005).

R. Surana, A. Pyne, M. Rani and R. Suryanarayanan. Measurement of enthalpic relaxation by differential scanning calorimetry – effect of experimental conditions. Thermochimica Acta 433: 173-182 (2005).

A. R. Sheth, S. Bates, F. X. Muller and D. J. W. Grant. Local structure in amorphous phases of piroxicam from powder X-ray diffractometry. Crystal Growth & Design 5: 571-578 (2005).

A. Saluja and D. S. Kalonia. Application of ultrasonic shear rheometer to characterize rheological properties of high protein concentration solutions at microliter volume. Journal of Pharmaceutical Sciences 94: 1161-1168 (2005).

A. K. Salameh and L. S. Taylor. Deliquescence in binary mixtures. Pharmaceutical Research 22: 318-324 (2005).

S. Rambhatla, J. P. Obert, S. Luthra, C. Bhugra and M. J. Pikal. Cake shrinkage during freeze drying: A combined experimental and theoretical study. Pharmaceutical Development and Technology 10: 33-40 (2005).

M. J. Pikal, S. Cardon, C. Bhugra, F. Jameel, S. Rambhatla, W. J. Mascarenhas and H. U. Akay. The nonsteady state modeling of freeze drying: In-process product temperature and moisture content mapping and pharmaceutical product quality applications. Pharmaceutical Development and Technology 10: 17-32 (2005).

J. D. Perez-Ramos, W. P. Findlay, G. Peck and K. R. Morris. Quantitative analysis of film coating in a pan coater based on in-line sensor measurements. AAPS PharmSciTech 6: (2005).

S. Lohani, Y. G. Zhang, L. J. Chyall, P. Mougin-Andres, F. X. Muller and D. J. W. Grant. Carbamazepine-2,2,2-trifluoroethanol (1/1). Acta Crystallographica Section E-Structure Reports Online 61: O1310-O1312 (2005).

M. Donoso and E. S. Ghaly. Prediction of tablets disintegration times using near-infrared diffuse reflectance spectroscopy as a nondestructive method. Pharmaceutical Development and Technology 10: 211-217 (2005).

Z. D. Dong, W. W. Brennessel, B. E. Padden, S. A. Schroeder, I. Prakash, I. Bishay, V. G. Young, E. J. Munson and D. J. W. Grant. Crystal structure and physical characterization of N-(3,3-dimethylbutyl)-L-alpha-aspartyl-L-phenylalanine, the hydrolysis product of neotame. Journal of Chemical Crystallography 35: 233-241 (2005).

S. Datta and D. J. W. Grant. Effect of supersaturation on the crystallization of phenylbutazone polymorphs. Crystal Research and Technology 40: 233-242 (2005).

S. Datta and D. J. W. Grant. Computing the relative nucleation rate of phenylbutazone and sulfamerazine in various solvents. Crystal Growth & Design 5: 1351-1357 (2005).

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