Pediatric Mini-Tablet Formulation Explored Using Juvenile Porcine Model in CPPR Project

CPPR student, Monika Lavan, along with her mentor Greg Knipp and fellow CPPR faculty, Stephen Byrn of Purdue University and CPPR industrial mentor, Scott Hostetler, published their findings on the pharmacokinetics of a pediatric mini-tablet formulation of lapatinib evaluated in the mini-pig model. See https://doi.org/10.1208/s12249-020-01891-x to read more.

CPPR Project Finds Factors Influencing Stability of Biologics Stored in Bottles

@Bruna Minatovicz (under the supervision of her doctoral mentor, @Bodhi Chaudhuri, from @UConnPharmacy) published their findings on the factors that influence the stability of a model enzyme during bulk freezing.  Fill volume, storage placement, and cooling rate were shown to be significant factors.  See more at https://doi.org/10.1208/s12249-021-02034-6 in @AAPSPharmSciTech. 

 

CPPR Semi-Annual Spring Scientific Conference is a Virtual Success

Eighty-eight scientists from 9 companies and 3 universities met virtually on May 24 and 25 to share findings on completed projects, updates on current research and proposals on new research. Final project reports were in the areas of 3D printing, tabletability, oral peptide delivery, and modeling of tablet disintegration and dissolution.  Project updates were presented by poster on lyophilized formulations, continuous manufacturing, modeling of fluid bed drying, nanoparticle freeze-drying, and imaging of lyophilized products.  Proposed areas of research included binder-excipient interactions, predicting oral absorption, monitoring protein structural changes, excipient impact on protein formulations.

CPPR Faculty, Dr. Lynne Taylor, is 2020 AAPS Dale Wurster Awardee

Dr. Lynne Taylor, Retter Professor of Pharmacy at Purdue University in the Department of Industrial and Physical Pharmacy, was honored by the American Association of Pharmaceutical Scientists with the Dale Wurster Research Award.   Awarded every other year, The Wurster Research Awards is for significant research contributions in pharmaceutics.  Dr. Taylor is the second CPPR faculty to be selected for the Wurster Award.  She joins Dr. Diane Burgess, the 2018 awardee. 


CPPR Fall Scientific Conference held virtually on Nov 9-11, 2020

Nearly 50 industrial scientists, faculty and students came together to share results, ideas, and proposals at the 25th anniversary meeting of the Kildsig Center for Pharmaceutical Processing Research.  Final reports of 4 projects, updates on 7 ongoing projects and 5 proposals were presented.  Participants moved in and out of virtual breakout rooms at the poster session.  Read more about the CPPR at https://cppr.uconn.edu.