At the Annual Meeting of the Midwest Chapter of the International Society of Lyophilization – Freeze Drying (ISLFD) on April 11, 2019, Lauren Fontana won top honors for her poster, “Raman Spectral Changes in Lyophilized Proteins for Screening Formulation Stability Rank Order”. Lauren, a doctoral student of Prof. Robin Bogner, was also selected to present a talk at the meeting on her CPPR project results.
In collaboration with a pharmaceutical company, CPPR faculty Diane Burgess and her CPPR student, Tingting Li, along with UCHC Dentisty faculty, Dr. Rajesh Lalla, have developed a formulation containing a local anesthetic and medium chain fatty acid for treatment of oral mucositis. The formulation is sprayed as a liquid and gels on contact to provide local, sustained relief of mouth ulcers resulting from cancer treatments. Read more.
Xiuling Lu, Associate Director of the Kildsig Center for Pharmaceutical Processing Research, was awarded the 2019 Robert L. McCarthy Faculty Service Award. In addition to her service to CPPR, Dr. Lu has developed student-learning assistance programs, serves the SinoAmerican Pharmaceutical Association, and much more……
Andre Beringhs (UConn), Bruna Minatovicz (UConn), Geoff Zhang (CPPR IAB from Abbvie), Bodhi Chaudhuri (UConn), and Xiuling Lu published their CPPR research findings on “Impact of Porous Excipients on the Manufacturability and Product Performance of Solid Self-Emulsifying Drug Delivery Systems” in AAPS PharmSci Tech, 19(7):3298-3310 (2018). 
Shreya Kulkarni, a doctoral candidate in the Bogner lab at UConn, was awarded one of six Tier I Baxter Young Investigator awards at the headquarters of Baxter in Illinois in October 2018.
Dana Moseson, graduate student in Lynne Taylor’s lab at Purdue University describe the characterization of residual crystallinity in hot melt extrudates down to the nanometer-scale using a suite of techniques. See Moseson DE, Mugheirbi NA, Stewart AA, Taylor LS. Nanometer-Scale Residual Crystals in a Hot Melt Extruded Amorphous Solid Dispersion: Characterization by Transmission Electron Microscopy. Crystal Growth & Design. 2018 Oct 26;18(12):7633-40.
Professor Tai-Hsi Fan (UConn Dept of Mechanical Engineering) along with colleagues at the UConn School of Pharmacy, Regeneron Pharmaceuticals, and MedImunne published an article describing “Phase-Field Modeling of Freeze Concentration of Protein Solutions” in the journal, Polymers (2019) Vol. 11, article 10.
Dana Moseson and her advisor Lynne Taylor from Purdue University published their CPPR-funded work on applying phase diagrams to prevent residual crystallinity in hot melt extrudates. See Moseson DE, Taylor LS. The application of temperature-composition phase diagrams for hot melt extrusion processing of amorphous solid dispersions to prevent residual crystallinity. International journal of pharmaceutics. 2018 Dec 20;553(1-2):454-66.
Shreya Kulkarni (UConn), Raj Suryanarayanan (UMinnesota), Joe Rinella (CPPR IAB Mentor from GSK) and Robin Bogner (UConn) published their CPPR research findings on “Mechanisms by which crystalline mannitol improves the reconstitution time of high concentration lyophilized protein formulations” in European Journal of Pharmaceutics and Biopharmaceutics, 131, 70-81 (2018).
Kweku Amponsah-Efah, grad student at the University of Minnesota, in Dr. Raj Suryanarayanan’s lab, received one of the 2018 International Pharmaceutical Excipients Council Foundation Graduate Student Scholarship Awards. The award was presented at the IPEC foundation dinner, at the 2018 AAPS annual meeting in Washington, D.C. on Nov. 4th. Kweku presented two posters: “Characterizing the nature of drug-polymer complexes in aqueous solution using analytical ultracentrifugation” and “Probing the temperature-dependence of structural relaxation times deep in the glassy state of amorphous pharmaceuticals.”
